Pacific Centre (officially CF Pacific Centre since 2015) is a shopping mall located in Vancouver, British Columbia, Canada. It is owned by Cadillac Fairview, the Ontario Pension Board, and the Workplace Safety and Insurance Board, and is managed by Cadillac Fairview.

Based on the number of stores, most of which are underground, it is the largest mall in Downtown Vancouver, with over 100 stores and shops, and the seventh-busiest mall in Canada, with 22.1 million annual visitors as of 2018.[3] The mall is directly connected to the Hudson's Bay department store, Vancouver Centre Mall, two SkyTrain subway stations, and the former Four Seasons Hotel Vancouver.

Built between 1971 and 1973, it was an unofficial Eaton Centre. It is a joint venture of Cemp Investments, Toronto Dominion Bank and T. Eaton Company Limited.[4] The Pacific Centre was home to an Eaton's department store, succeeded by Sears Canada after 2002 and vacated in the fourth quarter of 2012.[5] A Nordstrom store opened in its former space in 2015. The City of Vancouver approved a 53,700-square-metre (578,000 sq ft) expansion of Pacific Centre, including retail premises that will extend to the street on both sides of West Georgia Street, and a direct link connecting the shopping centre with the new Vancouver City Centre SkyTrain station on Granville Street. The link opened in August 2009 in conjunction with the opening of the Canada Line. On 20 January 2017, Cadillac Fairview announced an agreement to sell a 50 percent interest in its Vancouver properties, including Pacific Centre, to the Ontario Pension Board and Ontario's Workplace Safety and Insurance Board, each to hold a 25% stake. Cadillac Fairview, itself a subsidiary of the Ontario Teachers' Pension Plan, will retain the remaining 50% interest and continue to manage the properties.[1] The rotunda glass dome at the northeast corner of the intersection of West Georgia Street and Howe Street was redeveloped in the early 2020s. Cadillac Fairview constructed a new two-storey pavilion building with 1,300 square metres (14,000 sq ft) of floor area that included a new Apple flagship store.[6] Nordstrom's flagship store closed on 13 June 2023 as the company exited the Canadian market.